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Pleiotrophin (PTN), human recombinant | 4469
- SKU:
- 26-4469-GEN
- Availability:
- Usually shipped in 5 working days
Description
Human Pleiotrophin (PTN) also called HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN (Pleiotrophin) and MK (midkine) are structural homologs, and are highly conserved among species. PTN plays an important role in development processes and promotion of neurite extension. Recombinant human PTN is a His-tag fusion protein (17.3 kDa) containing 136 amino acid residues of the PTN.
4469 | Pleiotrophin PTN human recombinant DataSheet
Biomolecule/Target: Pleiotrophin
Synonyms: PTN, Heparin Affin Regulatory Protein, HARP, Heparin-binding growth factor-8, HBGF-8, Osteoblast-Specific Factor-1, OSF-1, Heparin-binding growth-associated molecule, HB-GAM, HBNF-1 Heparin-binding brain mitogen, Heparin-binding neurite outgrowth-promoting factor 1, HBBM, NEGF1.
Alternates names: IL-1F8, IL-1H2, IL-1 eta, IL-1F8
Taglines: A heparin-binding growth factor
NCBI Gene ID #: 26525
NCBI Gene Symbol: IL36B
Gene Source: Human
Accession #: Q9UBH0
Recombinant: Yes
Source: E. coli.
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).
Activity (Specifications/test method): Measured by its ability to induce IL-8 production by human PBMCs
Biological activity: Measured by its ability to induce IL-8 production by human PBMCs
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 17.3 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Amino acid sequence: MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE