Plerixafor | B2405

Plerixafor is a hematopoietic stem cell (HSC) mobilizer. It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin lymphoma and multiple myeloma. It inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).

Plerixafor is a hematopoietic stem cell (HSC) mobilizer. It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin lymphoma and multiple myeloma. It inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).

B2405 | Plerixafor DataSheet

Alternate Name/Synonyms: JKL 169, Mozobil, 1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene

Appearance: White to off-white solid

Formulation:

CAS Number: 110078-46-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₅₄N₈

Molecular Weight: 502.78

Cell-Permeable?: True

Purity: ≥98%

Solubilities: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A Hematopoietic Stem Cell Mobilizer

MDL Number: MFCD05662218

PubChem CID: 65015

SMILES: C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3

InChi: InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2

InChi Key: YIQPUIGJQJDJOS-UHFFFAOYSA-N