Description
A selective inhibitor of steroyl-CoA desaturase 1 (SCD1), the key enzyme in oleic acid biosynthesis. PluriSIn 1, induces ER stress, protein synthesis attenuation, and apoptosis in hPSCs (human pluripotent stem cells). Also prevents teratoma formation from tumorigenic undifferentiated cells.
PluriSIn 1 is a selective inhibitor of steroyl-CoA desaturase 1 (SCD1), the key enzyme in oleic acid biosynthesis. PluriSIn 1, induces ER stress, protein synthesis attenuation, and apoptosis in hPSCs (human pluripotent stem cells).
Alternate Name/Synonyms: 4-Pyridinecarboxylic acid, 2-phenylhydrazide; NSC-14613
Appearance: Off-white solid
Formulation: N/A
CAS Number: 91396-88-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₁₁N₃O
Molecular Weight: 213.24
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml) or EtOH (>15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective steroyl-CoA desaturase 1 (SCD1) inhibitor
MDL Number: N/A
PubChem CID: 225362
SMILES: C1=CC=C(C=C1)NNC(=O)C2=CC=NC=C2
InChi: InChI=1S/C12H11N3O/c16-12(10-6-8-13-9-7-10)15-14-11-4-2-1-3-5-11/h1-9,14H,(H,15,16)
InChi Key: HUDWXDLBWRHCKO-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |