PMF1 Antibody (Center) [APR04416G]

PMF1 Antibody (Center) [APR04416G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PMF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human PMF1.

Cellular Localisation: Nucleus. Chromosome, centromere, kinetochore Note=Associated with the kinetochore

Molecular Weight: 23339

Clone: Polyclonal

Gene Name: PMF1 {ECO:0000312|EMBL:AAH65031.1}

Gene ID: 100527963;11243

Function: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.

Summary: Tissue Location: Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Polyamine-modulated factor 1, PMF-1, PMF1 {ECO:0000312|EMBL:AAH650311}