PMPCA polyclonal Antibody | BS71389

PMPCA polyclonal Antibody | BS71389 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: PMPCA (peptidase (mitochondrial processing) alpha), also known as alpha-MPP, P-55, INPP5E or MPPA, is a 525 amino acid protein that belongs to the peptidase M16 family and exists as a heterodimer of alpha and beta subunits. Localizing to mitochondrial matrix, PMPCA cleaves transit peptides from mitochondrial protein precursors. PMPCA is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PMPCA polyclonal Antibody detects endogenous levels of PMPCA protein.

Molecular Weight: ~ 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: INPP5E; KIAA0123; MPPA; Alpha-MPP; P-55; α-MPP; MPP-α; MPPα;

Immunogen: Recombinant protein of human PMPCA.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: