Description
PMS2 Polyclonal Antibody | E-AB-13526 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: DNA mismatch repair gene homologue, DNA mismatch repair protein PMS2, H_DJ0042M02.9, HNPCC4, Mismatch repair endonuclease PMS2, Mismatch repair gene PMSL2, MLH4, PMS 2, PMS1 homolog 2 mismatch repair system, PMS1 protein homolog 2, PMS2, PMS2 postmeiotic segregation increased 2, PMS2 postmeiotic segregation increased 2 (S. cerevisiae), PMS2, PMS2CL, PMSL2, Postmeiotic segregation increased, S. cerevisiae, 2
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling
Background: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human PMS2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 96 kDa
Molecular Weight(Observed): N/A