PMVK monoclonal Antibody | MB64535

PMVK monoclonal Antibody | MB64535 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rat

Application: IF, WB

Application Range: WB 1:2000, IF 1:100

Background: This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: phosphomevalonate kinase

Molecular Weight: 21.8 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HUMPMKI; PMK; PMKA; PMKASE; POROK1

Immunogen: Full length human recombinant protein of human PMVK (NP_006547) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A