PNMA3 polyclonal Antibody | BS65589

PNMA3 polyclonal Antibody | BS65589 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,Rat,

Application: WB,

Application Range: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PNMA3 polyclonal Antibody detects endogenous levels of PNMA3 protein.

Molecular Weight: ~57kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MA3; MA5; MGC132756; MGC132758; Paraneoplastic antigen Ma3; Paraneoplastic cancer testis brain antigen; Paraneoplastic Ma antigen 3; PNMA 3; PNMA3; PNMA3_MOUSE.  

Immunogen: KLH conjugated synthetic peptide derived from mouse PNMA3:351-450/463

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: