PODXL Antibody | 13-496

PODXL Antibody | 13-496 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 287-526 of human PODXL (NP_005388.2) .

Research Area: Cancer, Cell Cycle, Signal Transduction, Stem Cell

Tested Application: WB, IF

Application: WB: 1:1000 - 1:2000
IF: 1:100 - 1:200

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: HepG2

Positive Control 3: SW480

Positive Control 4: HT-1080

Positive Control 5: 293T

Positive Control 6: Mouse heart

Molecular Weight: Observed: 95kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PODXL, Gp200, MGC138240, PCLP, PC, PCLP-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.