LBD
POMT1 Antibody (C-term) [APR03684G]
- SKU:
- LBD-APR03684G
- Availability:
- Usually ships in 5 working days
Description
POMT1 Antibody (C-term) [APR03684G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This POMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human POMT1.
Cellular Localisation: Endoplasmic reticulum membrane; Multi-pass membrane protein
Molecular Weight: 84881
Clone: Polyclonal
Gene Name: POMT1
Gene ID: 10585
Function: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient (PubMed:12369018, PubMed:14699049, PubMed:28512129) . Essentially dedicated to O-mannosylation of alpha- DAG1 and few other proteins but not of cadherins and protocaherins (PubMed:28512129) .
Summary: Tissue Location: Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB, FC
Dilution: IHC-P--1:100~500 WB--1:1000 FC--1:10~50
Synonyms: Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, POMT1