Pozelimab (C5) Antibody, Monoclonal | 10-937

Pozelimab (C5) Antibody, Monoclonal | 10-937 | Gentaur UK, US & Europe Distribution

Host: N/A

Reactivity: N/A

Homology: N/A

Immunogen: Homo sapiens / C5 [Homo sapiens]

Research Area: Drug Analogues

Tested Application: N/A

Application: N/A

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: >95%

Clonality: Monoclonal

Clone: N/A

Isotype: IgG4-kappa

Conjugate: Unconjugated

Physical State: N/A

Buffer: PBS buffer pH7.5

Concentration: N/A

Storage Condition: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for 1-2 weeks. Store at -20 ˚C for 12 months. Store at -80 ˚C for long term storage.

Alternate Name: REGN-3918

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Pozelimab is research-based, fully human monoclonal antibody, invented using Regeneron's proprietary VelocImmune technology, which aims to block the complement signaling pathway by binding to complement factor C5. It also prevents the destruction (hemolysis) of red blood cells that cause paroxysmal nocturnal hemoglobinuria and other disease symptoms.