Description
PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARg is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism, PPARg also modulates insulin sensitivity, cell proliferation and inflammation. The inhibition of PPARg transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARg.
3809 | PPAR gamma Antibody DataSheet
Antibody Target: PPAR
Target Alternative Name: PPARG, PPAR G, PPAR g, peroxisome proliferator activated receptor
Tag Line:
Category: PPAR
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse
Immunogen Sequence: Synthetic peptide surrounding amino acid 262 of human PPARg isoform CRA-c
Accession #: P37231
Gene ID: 5468
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot
Positive Control:
Application And Usages: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa band, corresponding to PPARg (isoform CRA-c) in samples from human and mouse origins. Reactivity to other species has not been tested.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Size: |
30 ug |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |