PPBP Antibody | 18-389

PPBP Antibody | 18-389 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-128 of human PPBP (NP_002695.1) .

Research Area: Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:500 - 1:1000
IHC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: Human serum

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 14kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, TC-2, Connective tissue-activating peptide III (1-81) , CTAP-III (1-81) , Beta-thromboglobulin, Beta-TG, Neutrophil-activating peptide 2 (74) , NAP-2 (74) , Neutrophil-activating peptide 2 (73) , NAP-2 (73) , Neutrophil-activating peptide 2, NAP-2, TC-1, Neutrophil-activating peptide 2 (1-66) , NAP-2 (1-66) , Neutrophil-activating peptide 2 (1-63) , NAP-2 (1-63) , PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.