LBD
PPFIA2 Antibody (Center) [AMM08664G]
- SKU:
- LBD-AMM08664G
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Description
PPFIA2 Antibody (Center) [AMM08664G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This PPFIA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the Central region of human PPFIA2.
Cellular Localisation: Cytoplasm. Cell surface. Cell projection, dendritic spine. Note=Colocalizes with PTPRF at the cell surface
Molecular Weight: 143291
Clone: Polyclonal
Gene Name: PPFIA2
Gene ID: 8499
Function: Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines (PubMed:30021165) .
Summary: Tissue Location: Expressed only in brain.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Liprin-alpha-2, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2, PTPRF-interacting protein alpha-2, PPFIA2