Description
PPIE Antibody | 22-668 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human PPIE (NP_006103.1) .
Research Area: Signal Transduction
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: THP-1
Positive Control 3: Jurkat
Positive Control 4: HL-60
Positive Control 5: Mouse testis
Positive Control 6: Mouse thymus
Molecular Weight: Observed: 33kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PPIE, CYP33, CYP-33
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.