PPIE Antibody | 22-668

PPIE Antibody | 22-668 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human PPIE (NP_006103.1) .

Research Area: Signal Transduction

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: THP-1

Positive Control 3: Jurkat

Positive Control 4: HL-60

Positive Control 5: Mouse testis

Positive Control 6: Mouse thymus

Molecular Weight: Observed: 33kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PPIE, CYP33, CYP-33

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.