PPP1R13L Antibody (Center) [ApR04848G]

PPP1R13L Antibody (Center) [ApR04848G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PPP1R13L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 455-485 amino acids from the Central region of human PPP1R13L.

Cellular Localisation: Cytoplasm. Nucleus Note=Predominantly cytoplasmic but also nuclear

Molecular Weight: 89091

Clone: Polyclonal

Gene Name: PPP1R13L

Gene ID: 10848

Function: Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540) .

Summary: Tissue Location: Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: RelA-associated inhibitor, Inhibitor of ASPP protein, Protein iASPP, NFkB-interacting protein 1, PPP1R13B-like protein, PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI