PPP1R8 Polyclonal Antibody | E-AB-61309

PPP1R8 Polyclonal Antibody | E-AB-61309 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: PPP1R8, ARD-1, ARD1, NIPP-1, NIPP1, PRO2047

Application: WB, IHC, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human PPP1R8 (NP_612568.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 13 kDa/22 kDa/38 kDa

Molecular Weight(Observed): 40 kDa