PRCC monoclonal Antibody | MB64617

PRCC monoclonal Antibody | MB64617 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1) (p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: papillary renal cell carcinoma (translocation-associated)

Molecular Weight: 52.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RCCP1; TPRC

Immunogen: Human recombinant protein fragment corresponding to amino acids 135-491 of human PRCC (NP_005964) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A