PRDX3 Antibody (C-term) [AMR09517G]

PRDX3 Antibody (C-term) [AMR09517G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This PRDX3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 229-262 amino acids from the C-terminal region of human PRDX3.

Cellular Localisation: Mitochondrion {ECO:0000250|UniProtKB:P35705}. Cytoplasm. Early endosome. Note=Localizes to early endosomes in a RPS6KC1-dependent manner.

Molecular Weight: 27693

Clone: Polyclonal

Gene Name: PRDX3

Gene ID: 10935

Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:7733872, PubMed:17707404) . Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:12492477) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Thioredoxin-dependent peroxide reductase, mitochondrial, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1