PRKAR1B Antibody | 13-443

PRKAR1B Antibody | 13-443 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-290 of human PRKAR1B (NP_002726.1) .

Research Area: Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Tested Application: WB

Application: WB: 1:1000 - 1:4000

Specificiy: N/A

Positive Control 1: U-251MG

Positive Control 2: HeLa

Positive Control 3: Jurkat

Positive Control 4: HepG2

Positive Control 5: BT-474

Positive Control 6: Mouse brain

Molecular Weight: Observed: 43kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: cAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1B

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA) , which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene.