PRKCDBP Antibody | 7269

PRKCDBP Antibody | 7269 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: Predicted species reactivity based on immunogen sequence: Rat: (100%)

Immunogen: Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP.
The immunogen is located within amino acids 150 - 200 of PRKCDBP.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB, IHC-P, IF

Application: PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: It is predicted to not cross-react with other members of the cavin family.

Positive Control 1: Cat. No. 1288 - A20 Cell Lysate

Positive Control 2: Cat. No. 10-901 - Human Spleen Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 29 kDa

Validation: N/A

Isoform: N/A

Purification: PRKCDBP Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PRKCDBP antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: PRKCDBP Antibody: SRBC, HSRBC, CAVIN3, cavin-3, SRBC, Protein kinase C delta-binding protein, Cavin-3, hSRBC

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP) , also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.