PRLR Antibody (Center) [AMR09546G]

PRLR Antibody (Center) [AMR09546G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PRLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the Central region of human PRLR.

Cellular Localisation: Membrane; Single-pass type I membrane protein

Molecular Weight: 69506

Clone: Polyclonal

Gene Name: PRLR

Gene ID: 5618

Function: This is a receptor for the anterior pituitary hormone prolactin (PRL) . Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Summary: Tissue Location: Expressed in breast, placenta, kidney, liver and pancreas.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Prolactin receptor, PRL-R, PRLR