LBD
PRLR Antibody (Center) [AMR09546G]
- SKU:
- LBD-AMR09546G
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Description
PRLR Antibody (Center) [AMR09546G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PRLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the Central region of human PRLR.
Cellular Localisation: Membrane; Single-pass type I membrane protein
Molecular Weight: 69506
Clone: Polyclonal
Gene Name: PRLR
Gene ID: 5618
Function: This is a receptor for the anterior pituitary hormone prolactin (PRL) . Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Summary: Tissue Location: Expressed in breast, placenta, kidney, liver and pancreas.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Prolactin receptor, PRL-R, PRLR