BW
PRMT5 Mouse monoclonal Antibody | MB9022
- SKU:
- BW-MB9022
- Availability:
- Usually ships in 5 working days
Description
PRMT5 Mouse monoclonal Antibody | MB9022 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:1000 IHC: 1:100-1:200
Background: PRMT5, also designated JAK-binding protein 1), (JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their Arginine- and Glycine-rich (RG) domains, while pICln binds the Sm domains. PRMT5 is a distinct member of the protein-Arginine methyltransferase (PRMT) family, and predominantly localizes to the cytoplasm in a wide variety of tissues. PRMT5 also associates specifically with the transcription start site region of the cyclin E1 promoter, and, therefore, is involved in the control of transcription and proliferation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of PRMT5 and does not cross-react with related proteins.
Molecular Weight: ~ 70 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Protein arginine N-methyltransferase 5; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1Hs; PRMT5; HRMT1L5; IBP72; JBP1; SKB1
Immunogen: This Antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of PRMT5.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A affinity purified
Pathway: Toll-like Receptor signaling,B cell receptor signaling,