PRMT8 Antibody (C-term) [APR30915G]

PRMT8 Antibody (C-term) [APR30915G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.

Cellular Localisation: Cell membrane; Lipid-anchor; Cytoplasmic side

Molecular Weight: 45291

Clone: Polyclonal

Gene Name: PRMT8 (HGNC:5188)

Gene ID: 56341

Function: S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer (PubMed:16051612, PubMed:17925405, PubMed:26876602, PubMed:26529540) . Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS (PubMed:18320585) .

Summary: Tissue Location: Brain-specific..

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein arginine N-methyltransferase 8, 211-, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, PRMT8, HRMT1L3, HRMT1L4