PRODH Antibody | 19-891

PRODH Antibody | 19-891 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4) .

Research Area: Apoptosis, Cancer, Cell Cycle, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: BT-474

Positive Control 2: MCF-7

Positive Control 3: U-251MG

Positive Control 4: A-673

Positive Control 5: Mouse liver

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 68kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PRODH, tumor protein p53 inducible protein 6, TP53I6, SCZD4, proline oxidase, mitochondrial, proline oxidase 2, proline dehydrogenase, proline dehydrogenase (oxidase) 1, PRODH2, PRODH1, POX, PIG6, p53-induced gene 6 protein, OTTHUMP00000196497, OTTHUMP00000196496, MGC148079, MGC148078, HSPOX2, FLJ33744, POX2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4) . This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.