Description
PRODH Antibody | 19-891 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4) .
Research Area: Apoptosis, Cancer, Cell Cycle, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: BT-474
Positive Control 2: MCF-7
Positive Control 3: U-251MG
Positive Control 4: A-673
Positive Control 5: Mouse liver
Positive Control 6: Mouse kidney
Molecular Weight: Observed: 68kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PRODH, tumor protein p53 inducible protein 6, TP53I6, SCZD4, proline oxidase, mitochondrial, proline oxidase 2, proline dehydrogenase, proline dehydrogenase (oxidase) 1, PRODH2, PRODH1, POX, PIG6, p53-induced gene 6 protein, OTTHUMP00000196497, OTTHUMP00000196496, MGC148079, MGC148078, HSPOX2, FLJ33744, POX2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4) . This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.