Prohibitin (PHB1) Antibody (N-term) [AMR09554G]

Prohibitin (PHB1) Antibody (N-term) [AMR09554G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This Prohibitin (PHB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the N-terminal region of human Prohibitin (PHB1) .

Cellular Localisation: Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane

Molecular Weight: 29804

Clone: Polyclonal

Gene Name: PHB (HGNC:8912)

Gene ID: 5245

Function: Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus (PubMed:11302691, PubMed:20959514, PubMed:28017329, PubMed:31522117) . Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner (By similarity) . Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells (By similarity) .

Summary: Tissue Location: Widely expressed in different tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB, FC

Dilution: IHC-P--1:100 WB--1:2000

Synonyms: Prohibitin, PHB