Prokineticin-2, Human Recombinant | P1006

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the testis and, in lower levels, in the small intestine. May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.

P1006 | Prokineticin-2 Human Recombinant DataSheet

Biomolecule/Target: Prokineticin-2

Synonyms: PK2, Protein Bv8 homolog, PROK2

Alternates names: A Proliferating-inducing Ligand, TNFSF13, TRDL-1

Taglines: A cysteine-rich secreted protein that function as an output molecule from the suprachiasmatic nucleus (SCN).

NCBI Gene ID #: 69583

NCBI Gene Symbol: APRIL

Gene Source: Mouse

Accession #: Q9D777

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by its ability to induce cell proliferation of activated T-cells.

Biological activity: Determined by its ability to induce cell proliferation of activated T-cells.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 21.9 kDa

Concentration: N/A

Appearance: Dry powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 5 and 100 mM Arginine.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-0.5 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: MRREVSRLQR SGGPSQKQGE RPWQSLWEQS PDVLEAWKDG AKSRRRRAVL TQKHKKKHSV LHLVPVNITS KDSDVTEVMW QPVLRRGRGL EAQGDIVRVW DTGIYLLYSQ VLFHDVTFTM GQVVSREGQG RRETLFRCIR SMPSDPDRAY NSCYSAGVFH LHQGDIITVK IPRANAKLSL SPHGTFLGFV KL