Proteasome Substrate II, Fluorogenic | B2059

Proteasome Substrate II is a sensitive fluorogenic substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Excitation: 380 nm. Emission: 460 nm

Proteasome Substrate II is a sensitive fluorogenic substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Excitation: 380 nm. Emission: 460 nm

B2059 | Proteasome Substrate II, Fluorogenic DataSheet

Alternate Name/Synonyms: Ac-RLR-AMC; Acetyl-Arg-Leu-Arg-7-amido-4-methylcoumarin; Proteasome Substrate

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: 929903-87-7 (free base)

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₄₆N₁₀O₆ .C₂HF₃O₂

Molecular Weight: 756.8

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A sensitive fluorogenic proteasome substrate

MDL Number: N/A

PubChem CID: 131676392

SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C

InChi: InChI=1S/C30H46N10O6/c1-16(2)13-23(40-27(44)21(37-18(4)41)7-5-11-35-29(31)32)28(45)39-22(8-6-12-36-30(33)34)26(43)38-19-9-10-20-17(3)14-25(42)46-24(20)15-19/h9-10,14-16,21-23H,5-8,11-13H2,1-4H3,(H,37,41)(H,38,43)(H,39,45)(H,40,44)(H4,31,32,35)(H4,33,34,36)/t21-,22-,23-/m0/s1

InChi Key: DOIHRXFNOWSOMS-VABKMULXSA-N