Protein Deglycase (DJ-1), human recombinant | P1130

DJ-1 is a multi-functional homodimeric protein involve in cancers and Parkinson’s disease. Human DJ-1 is a 19.9 kDa protein containing 189 amino acid residues.

P1130 | Protein Deglycase DJ-1 human recombinant DataSheet

Biomolecule/Target: PARK7

Synonyms: Park7, DJ1, Oncogene DJ1, Parkinson disease protein 7

Alternates names: TNFSF7, CD70

Taglines: A protein that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins.

NCBI Gene ID #: 939

NCBI Gene Symbol: CD27

Gene Source: Human

Accession #: P26842

Recombinant: Yes

Source: CHO cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors.

Biological activity: Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 19.2 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 20 mM Sodium Citrate, pH 3.0.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P