PRRT2 Antibody (Center) [APR31562G]

PRRT2 Antibody (Center) [APR31562G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PRRT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-233 amino acids from the Central region of human PRRT2.

Cellular Localisation: Cell membrane; Single-pass membrane protein {ECO:0000250|UniProtKB:E9PUL5}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250|UniProtKB:E9PUL5}; Single-pass membrane protein {ECO:0000250|UniProtKB:E9PUL5}. Cell junction, synapse {ECO:0000250|UniProtKB:E9PUL5}. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:D3ZFB6}. Cell junction, synapse, postsynaptic density membrane {ECO:0000250|UniProtKB:D3ZFB6}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:D3ZFB6}

Molecular Weight: 34945

Clone: Polyclonal

Gene Name: PRRT2

Gene ID: 112476

Function: As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca (2+) -sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Proline-rich transmembrane protein 2, Dispanin subfamily B member 3, DSPB3, PRRT2