PRSSL1 Antibody (C-term) [APR04484G]

PRSSL1 Antibody (C-term) [APR04484G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PRSSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human PRSSL1.

Cellular Localisation: Cytoplasmic granule lumen. Secreted. Note=Stored in cytoplasmic granules and secreted as active enzyme in response to stimulation of neutrophils.

Molecular Weight: 30334

Clone: Polyclonal

Gene Name: PRSS57

Gene ID: 400668

Function: Serine protease that cleaves preferentially after Arg residues (PubMed:22474388, PubMed:23904161, PubMed:25156428) . Can also cleave after citrulline (deimidated arginine) and methylarginine residues (PubMed:25156428) .

Summary: Tissue Location: Detected in peripheral blood neutrophil granulocytes, but not in other types of leukocytes. Detected in neutrophils and neutrophil precursors in bone marrow (at protein level) (PubMed:22474388, PubMed:23904161) . Detected in myeloblasts and promyelocytes in bone marrow (PubMed:23904161)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC, IF

Dilution: IF--1:25 FC--1:25 WB--1:4000

Synonyms: Serine protease 57, 3421-, Serine protease 1-like protein 1, PRSS57, PRSSL1