PSG1 polyclonal Antibody | BS8187

PSG1 polyclonal Antibody | BS8187 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC IF

Application Range: WB: 1:500 - 1:2000 IHC:1:50 - 1:100 IF:1:50 - 1:200

Background: Pregnancy specific glycoprotein 1 (PSG1), also designated CD66f, is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. 11 human PSG proteins (PSG1-PSG11) have been described.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1

Molecular Weight: ~ 55-72 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Pregnancy-specific beta-1-glycoprotein 1; PS-beta-G-1; PSBG-1; Pregnancy-specific glycoprotein 1; CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; Pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD66f; PSG1; B1G1; PSBG1; PSGGA

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Tumor Angiogenesis,