PSMA3 Polyclonal Antibody | E-AB-18804

PSMA3 Polyclonal Antibody | E-AB-18804 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HC8, Macropain subunit C8, MGC12306, MGC32631, Multicatalytic endopeptidase complex subunit C8, Proteasome (prosome macropain) subunit alpha type 3, Proteasome alpha 3 subunit, Proteasome component C8, Proteasome subunit alpha type 3, Proteasome subunit alpha type-3, Proteasome subunit C8, PSA3, PSC8, psmA3

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human PSMA3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 28 kDa

Molecular Weight(Observed): Refer to figures