LDB
PSMA5 Antibody (Ascites) [AMM02406G]
- SKU:
- LBD-AMM02406G-GEN
- Availability:
- Usually ships in 5 working days
Description
PSMA5 Antibody (Ascites) [AMM02406G] | Gentaur UK, US & Europe Distribution
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: Purified His-tagged PSMA5 protein (Fragment) was used to produced this monoclonal antibody.
Cellular Localisation: Cytoplasm. Nucleus
Molecular Weight: 26411
Clone: Monoclonal
Gene Name: PSMA5
Gene ID: 5686
Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin- independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) .
Summary: Tissue Location: Expressed in fetal brain (at protein level) .
Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000~6400
Synonyms: Proteasome subunit alpha type-5, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain, PSMA5