PSMA6 Antibody (N-Term) [ApR04893G]

PSMA6 Antibody (N-Term) [ApR04893G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This PSMA6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from human PSMA6.

Cellular Localisation: Cytoplasm. Nucleus. Note=Colocalizes with TRIM5 in cytoplasmic bodies. {ECO:0000250|UniProtKB:Q9QUM9}

Molecular Weight: 27399

Clone: Polyclonal

Gene Name: PSMA6

Gene ID: 5687

Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin- independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Proteasome subunit alpha type-6, 27 kDa prosomal protein, PROS-27, p27K, Macropain iota chain, Multicatalytic endopeptidase complex iota chain, Proteasome iota chain, PSMA6, PROS27