Description
PSMA6 Polyclonal Antibody | E-AB-19189 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: 27 kDa prosomal protein, IOTA, Macropain iota chain, Macropain subunit iota, MGC22756, MGC2333, MGC23846, Multicatalytic endopeptidase complex iota chain, p27K, PROS 27, PROS-27, PROS27, Prosomal P27K protein, Proteasome (prosome macropain) subunit alpha type 6, Proteasome iota chain, Proteasome subunit alpha type 6, Proteasome subunit alpha type-6, Proteasome subunit iota, PSA6, PSMA 6, PSMA6
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.
Concentration: 1.56 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human PSMA6
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 27 kDa
Molecular Weight(Observed): Refer to figures