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PSMA6 (Proteasome 20S alpha 6) monoclonal Antibody | MB64665

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BW-MB64665
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Description

PSMA6 (Proteasome 20S alpha 6) monoclonal Antibody | MB64665 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: FC, IHC, WB

Application Range: WB 1:500~2000, IHC 1:150, FLOW 1:100

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: proteasome subunit alpha 6

Molecular Weight: 27.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: IOTA; p27K; PROS27

Immunogen: Full length human recombinant protein of human PSMA6 (NP_002782) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A

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