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PSMB9 (Proteasome 20S LMP2) monoclonal Antibody | MB64678
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- BW-MB64678
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Description
PSMB9 (Proteasome 20S LMP2) monoclonal Antibody | MB64678 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: FC, WB
Application Range: WB 1:500~2000, FLOW 1:100
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex) . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: proteasome subunit beta 9
Molecular Weight: 23.1 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: beta1i; LMP2; PSMB6i; RING12
Immunogen: Human recombinant protein fragment corresponding to amino acids 21-219 of human PSMB9 (NP_002791) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A