PSMB9 (Proteasome 20S LMP2) monoclonal Antibody | MB64680

PSMB9 (Proteasome 20S LMP2) monoclonal Antibody | MB64680 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, IHC, WB

Application Range: WB 1:2000, IHC 1:150, FLOW 1:100

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex) . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: proteasome subunit beta 9

Molecular Weight: 23.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: beta1i; LMP2; PSMB6i; RING12

Immunogen: Human recombinant protein fragment corresponding to amino acids 21-219 of human PSMB9 (NP_002791) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A