PSMC1 polyclonal Antibody | BS8005

PSMC1 polyclonal Antibody | BS8005 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IHC

Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Background: Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodesthe presinilin 1 (PSEN1) gene,which is one of the three key genes associated with the development of Alzheimer’s disease. The SERPINA1 gene islocated on chromosome 14 and when defective leadsto the genetic disorder α1-antitrypsin deficiency. This disorder is characterized bysevere lung complications and liver dysfunction. Notably, the immunoglobulin heavychain locusisfoundon chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the translocationsfound in a variety of B cellmalignancies. The PSMC1 gene product has been provisionally designated PSMC1 pending furthercharacterization.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PSMC1 polyclonal Antibody detects endogenous levels of PSMC1 protein.

Molecular Weight: ~ 58 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 26S protease regulatory subunit 4; P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1; PSMC1

Immunogen: Recombinant full length Human PSMC1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: