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PSME4 polyclonal Antibody | BS72116
- SKU:
- BW-BS72116
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- Usually ships in 5 working days
Description
PSME4 polyclonal Antibody | BS72116 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC
Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200
Background: Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PSME4 polyclonal Antibody detects endogenous levels of PSME4 protein.
Molecular Weight: 211kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PA200
Immunogen: Recombinant protein of human PSME4
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: