PTPN18 Polyclonal Antibody | E-AB-67993

PTPN18 Polyclonal Antibody | E-AB-67993 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: PTPN18, BDP1, PTP-HSCF

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human PTPN18 (NP_001135842.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 38 kDa/50 kDa

Molecular Weight(Observed): 60 kDa