PTPRM Polyclonal Antibody | E-AB-12853

PTPRM Polyclonal Antibody | E-AB-12853 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: hR PTPu, Protein tyrosine phosphatase mu, Protein tyrosine phosphatase receptor type M, Protein tyrosine phosphatase receptor type mu polypeptide, Protein-tyrosine phosphatase mu, PTPRL1, Ptprm, PTPRM, R PTP mu, R-PTP-mu, Receptor type tyrosine protein phosphatase mu, Receptor-type tyrosine-protein phosphatase mu, RPTPM, RPTPU

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PTPRM

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A