LBD
PURB Antibody (C-term) [APR30888G]
- SKU:
- LBD-APR30888G
- Availability:
- Usually ships in 5 working days
Description
PURB Antibody (C-term) [APR30888G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PURB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-289 amino acids from the C-terminal region of human PURB.
Cellular Localisation: Nucleus.
Molecular Weight: 33241
Clone: Polyclonal
Gene Name: PURB
Gene ID: 5814
Function: Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity) .
Summary: Tissue Location: Expressed in myocardium of heart failure patients.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IF, FC
Dilution: WB--1:1000
Synonyms: Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB