Purified Anti-Human CD4 Monoclonal Antibody | DL21322F

Purified Anti-Human CD4 Monoclonal Antibody | DL21322F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: T-cell surface glycoprotein CD4, CD4, T-cell surface antigen T4/Leu-3, CD4

Reactivity: Human

Application: FCM, IHC, IF

Background: CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7) .

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: RPA-T4

Isotype: Mouse IgG1, κ