Purified Anti-Human/Monkey CD154 Monoclonal Antibody | DL21619F

Purified Anti-Human/Monkey CD154 Monoclonal Antibody | DL21619F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: CD40L, gp39, TRAP, T-BAM, TNFSF5

Reactivity: Human, Monkey

Application: FCM, IP

Background: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Concentration: 0.2 mg/mL

Conjugation: Unconjugated

Buffer: PBS with 0.05% Proclin300

Clone: 5C8

Isotype: Mouse IgG2a, κ