DVLP
Purified Anti-Mouse CD132 Monoclonal Antibody | DL20287F
- SKU:
- DLVP-DL20287F
- Availability:
- Usually ships in 5 working days
Description
Purified Anti-Mouse CD132 Monoclonal Antibody | DL20287F | Gentaur UK, US & Europe Distribution
Host: Rat
Synonyms: Cytokine receptor common subunit gamma, Il2rg, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132
Reactivity: Mouse
Application: FCM
Background: CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID) .
Concentration: 0.2 mg/mL
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Clone: 3E12
Isotype: Rat IgG2b, κ